Ukrainian pharmaceutical company Microkhim (Rubizhne, Luhansk region) is ready to start production of a generic antiviral drug to combat the coronavirus disease (COVID-19) by the end of the year, Microkhim Director General Ihor Pohromsky has said in an interview with the Uriadovy Kurier government’s newspaper. “Now the key point is that we are transporting the substance. In the near future we will expose it to comprehensive analytical control, develop a dosage form and establish and conduct bioequivalence clinical trials. There is a lot of work ahead. There is a lot of professional work that we can do, but it has terms and limitations. However, the situation is such that, despite quarantine, we are ready to work to provide the country with a domestic drug this year, and I am sure that we will be first among national manufacturers, who will develop it,” he said, adding that it comes to the production of generic Avigan.
According to Pohromsky, “the drug was developed in Japan against several influenza viruses in 2014, and in 2015 it passed the third phase of clinical trials in the United States. It happened so that it was tested during an epidemic in Wuhan, and later allowed for experimental use in Italy against COVID-19. By the way, it has already become known that more than 30 countries have asked Japan to provide them with this drug for combating COVID-19. Japan has provided it to Ukraine to continue clinical trials involving patients with COVID-19.”
The general director said that the price of the generic drug made in Ukraine will be much lower than the price of the original. In addition, in the context of global hype, it is difficult to talk about the wholesale supply of original drugs to Ukraine. Therefore, according to Pohromsky, it is necessary to start domestic production.
CORONAVIRUS, GENERIC, MICROKHIM, PRODUCTION
