CSD LAB Medical Laboratory has introduced pharmacogenetic laboratory diagnostics services.
As the laboratory told Interfax-Ukraine, CSD LAB offers two tests that will allow individualizing the treatment of many diseases. In particular, the laboratory conducts a PCR test that determines sensitivity to warfarin. The test helps to prevent and reduce the risk of bleeding as a result of warfarin therapy by up to 50%.
Warfarin therapy is used for the treatment and prevention of deep vein thrombosis and pulmonary embolism, for the secondary prevention of myocardial infarction and prevention of thromboembolic complications (stroke or systemic embolism) after myocardial infarction in patients with heart failure or prosthetic heart valves, prevention of dynamic cerebrovascular disease and stroke, and prevention of postoperative thrombosis.
In addition, CSD Lab has implemented a pharmacogenetic test that allows to determine variations in the CYP2C19 gene. This gene is a clinically important enzyme involved in the biotransformation of a number of antidepressants, anticoagulants, and antimycotic drugs. The test helps to identify and adjust antiplatelet therapy for a number of diseases.
“The main goal of pharmacogenetics is to use the patient’s individual genetic information to inform and prescribe the most effective type and dose of drugs. Targeted diagnostics and treatment of a patient can be determined according to the results of the study of his or her genetic profile, which makes pharmacotherapy for patients as effective, safe and affordable as possible,” CSD LAB emphasized.
At the same time, the laboratory emphasizes that pharmacotherapy based on the principles of personalized medicine is a relatively new area in medicine in general. The essence of personalized medicine is the individualization of drug therapy. Pharmacogenetics seeks to identify genes and their variants that determine the adequacy of pharmacotherapy and reduce the risk of side effects.
“The new approach is to test patients for possible reactions to the use of new drugs and to formulate a treatment based on the test results,” the laboratory emphasized.
CSD LAB plans to hold a course of lectures on pharmacogenetics for doctors in the fall.
CSD LAB is one of the leading laboratories in Ukraine that provides more than 1500 tests: from a complete blood count to the determination of genetic disorders in a tumor using NGS. It has been one of the largest pathology laboratories in Eastern Europe for 13 years.
