Filatov Institute of Eye Diseases and Tissue Therapy of the National Academy of Medical Sciences of Ukraine (Odessa, Ukraine) received as humanitarian aid the drug melphalan for the treatment of retinoblastoma, an intraocular malignant tumor in children.
As the Interfax-Ukraine agency was informed at the clinic, the drug is used to treat this tumor with the Institute’s own combined polychemotherapy method which implies injecting the drug directly into the tumor in combination with general polychemotherapy. This method allows to save the eye affected by the tumor and even vision in 80% of cases, including those with retinoblastoma stage 3-4.
The drug used for intraocular injections is melphalan, which is produced by Aspen Pharmacare Holdings Limited.
“Unfortunately, recently it has been impossible to purchase melphalan for injections in Ukraine. The institute has taken active steps to obtain the drug,” the institute reported.
Obtaining the drug was made possible thanks to the efforts of Olga Nikitchenko, head of the patronage service of the Ukrainian Ministry of Foreign Affairs, Ukrainian Ambassador to South Africa Lubov Abravitova, and Stavros Nikolau, senior executive director of Aspen Group, with support from the We Stand with Ukraine Foundation.
“The drug was delivered to the Filatov Institute. And literally the next day the first patient received treatment to save his vision and life,” the clinic reported.
Retinoblastoma is an intraocular highly malignant retinal tumor that develops mainly in children in the first two years of life and accounts for 89.3% to 98.2% of all intraocular neoplasms in children. Retinoblastoma incidence rate in the world is currently 1 case per 10-15 thousands newborns.
Due to asymptomatic course of the disease the majority of children (85-86%) come to the clinics with far advanced stage of retinoblastoma and even up to now many clinics have considered that the only way to save the life of the child was to remove the tumor together with the eye.
Retinoblastoma treatment in Ukraine is carried out at the Department of Pediatric Ophthalmopathology of the Institute of Eye Diseases and Tissue Therapy named after Filatov Institute of Eye Diseases and Tissue Therapy. V.P.Filatov Institute of Eye Diseases and Tissue Therapy of NAMS of Ukraine”. In recent years, the clinic has treated about 300 children with retinoblastoma aged from three months to eight years. One child receives from three to 20 injections, depending on the stage of the disease.
